AN EXPERIMENTAL STUDY ON THE HEAT ENHANCEMENT AND THE BIO-HEAT TRANSFER USING GOLD MACRO ROD AND ULTRASOUND: A POTENTIAL ALTERNATIVE TO KILL CANCER CELLS

Abstract

We have previously proposed a method of treating solid tumors with a combination of gold macro-rods irradiated with ultrasound. Macro particle sized rods offer a greater circumferential treatment area over nanoparticle options. Experimental studies were conducted to investigate the heat enhancement and the bio-heat transfer to breast chicken using gold macro rod and ultrasound. An ultrasound, other than a focused ultrasound, may produce heat enough to cook a chicken breast up to about 1 cm diameter if a single gold rod is placed on the superficial tissue. Simulations and experimental results will provide the means to evaluate the treatment, to better design a patient-specific therapy to achieve maximum destruction of tumor and injury minimization of healthy tissue by controlling size, shape and location of gold seeds and ultrasound parameters.