The Anti-Nociceptive/Anti-Inflammatory Actions of Botulinum Toxin A for the Treatment of Chronic Pain: A Literature Review
- 1 Saint-Joseph University, Lebanon
Abstract
The aim of this article is to describe the new actions of botulinum toxin A for chronic pain treatment. BT/A inhibits the exocytosis of synaptic vesicles containing the pain mediators neurotransmitters, reduces the post traumatic trigeminal neuralgia pain, inhibits the release of microglia derived TNF-α as well as other pro inflammatory cytokines, viable treatment option in the case of patients who do not respond to conservative treatment methods of chronic pain (medication) BT/A is an emerging treatment for chronic pain; patients with severe chronic facial pain, not responding to conventional treatments, can respond to botulinum type a injections
DOI: https://doi.org/10.3844/crdsp.2021.62.70
Copyright: © 2021 Racha Hajj and Camille Haddad. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Anti Inflammatory
- Anti Nociceptive
- BiTox/AA
- Botulinum Toxin A
- Chronic Pain
- Derm-BOT