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Frequency: Quarterly
ISSN: 1553-6203 (Print)
ISSN: 1558-6340 (Online)
Research Article Open Access

Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals

Livia Maria Gonçalves Rossi1 and Paula Rahal1
  • 1 São Paulo State University, Brazil

Abstract

Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.

American Journal of Infectious Diseases
Volume 10 No. 4, 2014, 179-183

DOI: https://doi.org/10.3844/ajidsp.2014.179.183

Submitted On: 22 December 2014 Published On: 7 January 2015

How to Cite: Gonçalves Rossi, L. M. & Rahal, P. (2014). Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals. American Journal of Infectious Diseases, 10(4), 179-183. https://doi.org/10.3844/ajidsp.2014.179.183

Open AccessCopyright: © 2014 Livia Maria Gonçalves Rossi and Paula Rahal. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Hepatitis C Virus
  • Resistant Mutants
  • Therapy
  • Direct Acting-Antiviral