EFFICACY OF HONEY BEE AND FAGOPYRUM ESCULENTUM MOENCH OINTMENT IN THE TREATMENT OF SUB CHRONIC WOUND IN RABBITS: A CASE CONTROL STUDY

Abstract

The present study was undertaken to evaluate the efficacy of an ointment of honey bee and Fagopyrum esculentum Moench in the management of large dermal wound in a male rabbit wounded accidently. The wound was covered entirely by honey and then the fine powder of buckwheat grains was added. The treatment was applied once a day until complete epithelization has taken place. The results showed a complete resorption of inflammatory exsudate of wound at 4th day. The percentage of wound contraction has shown a rate of 5.55% at the 4th, it has risen to 32.22 and 71.48% at days 7 and 11 respectively to register 99.53% at the 26th days. The epithelization period was 27 days with a mean healing rate of 200 mm2 day-1. The study concludes that the ointment of honey and buckwheat stimulate the healing process in dermal wounds particularly in term of wound contraction. Other studies are underway to understand the possible implication of some amino acids as lysine, proline and glycine presented in buckwheat in the collagen synthesis process.